عناصر مشابهة
Effect Curcumin Plant on Liver of Rats Treated with Trichloethylene
| المصدر: | مجلة التربوي |
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| الناشر: |
جامعة المرقب - كلية التربية بالخمس
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| المؤلف الرئيسي: | |
| مؤلفين آخرين: | |
| المجلد/العدد: | ع12 |
| محكمة: | نعم |
| الدولة: | ليبيا |
| التاريخ الميلادي: | 2018 |
| الصفحات: | 321 - 328 |
| ISSN: | 2011-421X |
| رقم MD: | 879496 |
| نوع المحتوى: | بحوث ومقالات |
| اللغة: | English |
| قواعد المعلومات: | EduSearch |
| مواضيع: | |
| رابط المحتوى: |
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| المستخلص: | Background & Aims: Curcumin (CCM), a plant phenolic compound, is widely used as a spice and coloring agent in food. Recently, CCM, had been considered to possess antioxidant activities. This study aimed to investigate whether CCM, protect against trichloroethylene (TCE)- induced hepatotoxicity and to demonstrate its possible mode of action. Methods: A group of male rats were treated with TCE (5mg/1000 ml of drinking water) to induce liver injury. The CCM group was fed 25 g mixed with the diet (2.5Kg) concomitantly with 5 mg TCE/1000ml drinking water, for 8 weeks. The rat were killed after treatment period of 8 weeks, and samples of livers tissue were fixed immediately in 10% formalin. Results: Histopathological changes It was obviose that TCE administration has shown dramatic injures in the liver tissues, and the treatment with curcumin can activate these injures to advanced level. |
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