عناصر مشابهة
Synthesis of 4- (4-Acetamidobenzoyl ) -2-Oxirane Carboxylic Acid And Synthesis of Some Heterocyclic Compounds with Non-Mixed and Mixed System
المصدر: | مجلة العلوم الإنسانية والتطبيقية |
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الناشر: |
الجامعة الأسمرية الإسلامية زليتن - كليتى الآداب والعلوم
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المؤلف الرئيسي: | |
المجلد/العدد: | ع28 |
محكمة: | نعم |
الدولة: | ليبيا |
التاريخ الميلادي: | 2016 |
الصفحات: | 183 - 189 |
رقم MD: | 829463 |
نوع المحتوى: | بحوث ومقالات |
اللغة: | English |
قواعد المعلومات: | HumanIndex |
مواضيع: | |
رابط المحتوى: |
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المستخلص: | The present work deals with the reaction of 4-(4-Acetyl amino phenyl-4-oxobut-2-enoic acid (1) with hydrogen peroxide afforded oxirane derivative ( 2).The latter compound was treated with 2-amino – 5 – phenyl -1, 3, 4-thiadiazole to yield imidazole (3) .The new heterocyclic compounds( 4,5) are used as a key starting materials, reaction of (2) with amines, hydrazines, active methylene compounds and Friedel—Crafts reactions have been studied to synthesize some hetrocycles include derivatives. Also, (2) reacted with acetic acid. The structure of the newly synthesized compounds were elucidated by elemental analysis and spectroscopic data. |
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