عناصر مشابهة
Comparison between Fructose Amine and Hemoglobin A1C Level to Evaluate Glycemic Control in Sudanese Diabetic Control
| المصدر: | مجلة جامعة أم درمان الإسلامية |
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| الناشر: |
جامعة أم درمان الإسلامية - معهد البحوث والدراسات الإستراتيجية
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| المؤلف الرئيسي: | |
| مؤلفين آخرين: | |
| المجلد/العدد: | ع35 |
| محكمة: | نعم |
| الدولة: | السودان |
| التاريخ الميلادي: | 2022 |
| التاريخ الهجري: | 1443 |
| الصفحات: | 70 - 79 |
| ISSN: | 1858-5361 |
| رقم MD: | 1263609 |
| نوع المحتوى: | بحوث ومقالات |
| اللغة: | English |
| قواعد المعلومات: | IslamicInfo |
| مواضيع: | |
| رابط المحتوى: |
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| المستخلص: | Background: Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic diseases with high blood sugar levels over a prolonged period, and is one of the most severe and frequent human disorders. Fructosamine is a generic name given to a compound known as plasma protein ketoamines. Fructosamine together with glycated haemoglobin (HbA1c) are used to monitor the state of hyperglycaemia in diabetics. Objectives: This study aimed to compare between HeamoglobinA1c and Fructosamine in Sudanese diabetic patients in Omdurman Teaching Hospital and Diabetic and Endocrine center in Bahri. Materials and Methods: This is a cross-sectional study. Automated colorimetric determination of fructosamine for each of the 50 blood samples of the study group was carried out according to specific procedure. Latex enhanced immuno-assay method for hemoglobinA1c (HbA1c) determination based on the interaction between antigen molecules (HbA1c) and HbA1c specific c antibodies coated on latex beads was carried out according to a specific procedure. Control group criteria should be clear because it is confused. Results: HbA1c% and Fructose amine were measured on the same sample in 50 diabetic patients. There is a significantly direct positive correlation between levels of fructose amine (mmol/L) and HbA1c% among the studied group (P-value= 0.001<0.05). Sensitivity and specificity of fructosamine and HbA1c to detect blood glucose. hemoglobin A1C has (86%) sensitivity and (25%) specificity while fructosamine has (63%) sensitivity and (55%) specificity. Conclusion: In diabetes serum fructosamine assay can better reflect average blood glucose concentration over the previous 2-3 weeks and HbA1c is better reflective over the previous 8-10 weeks there for fructosamine can be used as routine test while HbA1C as a first -line screening test. |
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